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Ketamine-Induced Changes in the Signal and Noise of Rule Representation in Working Memory by Lateral Prefrontal Neurons

Working memory dysfunction is an especially debilitating symptom in schizophrenia. The NMDA antagonist ketamine has been successfully used to model working memory deficits in both rodents and nonhuman primates, but how it affects the strength and the consistency of working memory representations rem...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Ma, Liya, Skoblenick, Kevin, Seamans, Jeremy K., Everling, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605233/
https://ncbi.nlm.nih.gov/pubmed/26290238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1839-15.2015
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