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NMDA Antagonist Ketamine Reduces Task Selectivity in Macaque Dorsolateral Prefrontal Neurons and Impairs Performance of Randomly Interleaved Prosaccades and Antisaccades

Ketamine, an NMDA receptor antagonist, has been shown to induce behavioral abnormalities in humans that mimic the positive, negative, and most importantly cognitive deficits observed in schizophrenia. Similar cognitive deficits have been observed in nonhuman primates after a subanesthetic dose of ke...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Skoblenick, Kevin, Everling, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6621508/
https://ncbi.nlm.nih.gov/pubmed/22933786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1510-12.2012
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