The Complement Receptor C5aR Controls Acute Inflammation and Astrogliosis following Spinal Cord Injury

This study investigated the role of the complement activation fragment C5a in secondary pathology following contusive spinal cord injury (SCI). C5ar(−/−) mice, which lack the signaling receptor for C5a, displayed signs of improved locomotor recovery and reduced inflammation during the first week of...

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Udgivet i:J Neurosci
Main Authors: Brennan, Faith H., Gordon, Richard, Lao, Hong W., Biggins, Patrick J., Taylor, Stephen M., Franklin, Robin J.M., Woodruff, Trent M., Ruitenberg, Marc J.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2015
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605214/
https://ncbi.nlm.nih.gov/pubmed/25904802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5218-14.2015
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