Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties

Anxiety-related psychiatric disorders represent one of the largest health burdens worldwide. Single nucleotide polymorphisms of the FK506 binding protein 51 (FKBP51) gene have been repeatedly associated with anxiety-related disorders and stress sensitivity. Given the intimate relationship of stress...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Hartmann, Jakob, Wagner, Klaus V., Gaali, Steffen, Kirschner, Alexander, Kozany, Christian, Rühter, Gerd, Dedic, Nina, Häusl, Alexander S., Hoeijmakers, Lianne, Westerholz, Sören, Namendorf, Christian, Gerlach, Tamara, Uhr, Manfred, Chen, Alon, Deussing, Jan M., Holsboer, Florian, Hausch, Felix, Schmidt, Mathias V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605153/
https://ncbi.nlm.nih.gov/pubmed/26085626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4024-14.2015
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