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Accumulation of Laminin Monomers in Drosophila Glia Leads to Glial Endoplasmic Reticulum Stress and Disrupted Larval Locomotion

The nervous system is surrounded by an extracellular matrix composed of large glycoproteins, including perlecan, collagens, and laminins. Glial cells in many organisms secrete laminin, a large heterotrimeric protein consisting of an α, β, and γ subunit. Prior studies have found that loss of laminin...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Petley-Ragan, Lindsay M., Ardiel, Evan L., Rankin, Catharine H., Auld, Vanessa J.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604820/
https://ncbi.nlm.nih.gov/pubmed/26818504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1797-15.2016
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