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Accumulation of Laminin Monomers in Drosophila Glia Leads to Glial Endoplasmic Reticulum Stress and Disrupted Larval Locomotion

The nervous system is surrounded by an extracellular matrix composed of large glycoproteins, including perlecan, collagens, and laminins. Glial cells in many organisms secrete laminin, a large heterotrimeric protein consisting of an α, β, and γ subunit. Prior studies have found that loss of laminin...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Petley-Ragan, Lindsay M., Ardiel, Evan L., Rankin, Catharine H., Auld, Vanessa J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604820/
https://ncbi.nlm.nih.gov/pubmed/26818504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1797-15.2016
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