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The Curtius Rearrangement: Applications in Modern Drug Discovery and Medicinal Chemistry
The Curtius rearrangement is the thermal decomposition of an acyl azide derived from carboxylic acid to produce an isocyanate as the initial product. The isocyanate can undergo further reactions to provide amines and their derivatives. Due to its tolerance for a large variety of functional groups an...
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| Pubblicato in: | ChemMedChem |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6604631/ https://ncbi.nlm.nih.gov/pubmed/30187672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201800518 |
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