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The Curtius Rearrangement: Applications in Modern Drug Discovery and Medicinal Chemistry

The Curtius rearrangement is the thermal decomposition of an acyl azide derived from carboxylic acid to produce an isocyanate as the initial product. The isocyanate can undergo further reactions to provide amines and their derivatives. Due to its tolerance for a large variety of functional groups an...

詳細記述

保存先:
書誌詳細
出版年:ChemMedChem
主要な著者: Ghosh, Arun K., Brindisi, Margherita, Sarkar, Anindya
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604631/
https://ncbi.nlm.nih.gov/pubmed/30187672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201800518
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