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The Curtius Rearrangement: Applications in Modern Drug Discovery and Medicinal Chemistry
The Curtius rearrangement is the thermal decomposition of an acyl azide derived from carboxylic acid to produce an isocyanate as the initial product. The isocyanate can undergo further reactions to provide amines and their derivatives. Due to its tolerance for a large variety of functional groups an...
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| 出版年: | ChemMedChem |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6604631/ https://ncbi.nlm.nih.gov/pubmed/30187672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201800518 |
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