Long non-coding RNA PVT1 knockdown suppresses fibroblast-like synoviocyte inflammation and induces apoptosis in rheumatoid arthritis through demethylation of sirt6

BACKGROUND: As a type of chronic autoimmune joint disease, rheumatoid arthritis (RA) is a disorder, characterized by a variety of physical symptoms as well as RA fibroblast-like synoviocyte (RA-FLS) proliferation. More recently, long non-coding RNAs (lncRNAs) have been implicated in the progression...

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Vydáno v:J Biol Eng
Hlavní autoři: Zhang, Chun-Wang, Wu, Xia, Liu, Dan, Zhou, Wei, Tan, Wei, Fang, Yu-Xuan, Zhang, Yu, Liu, Yan-Qing, Li, Guo-Qing
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604378/
https://ncbi.nlm.nih.gov/pubmed/31303891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-019-0184-1
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