Avibactam Sensitizes Carbapenem-Resistant NDM-1–Producing Klebsiella pneumoniae to Innate Immune Clearance

Infections caused by New Delhi metallo-β-lactamase (NDM)–producing strains of multidrug-resistant Klebsiella pneumoniae are a global public health threat lacking reliable therapies. NDM is impervious to all existing β-lactamase inhibitor (BLI) drugs, including the non–β-lactam BLI avibactam (AVI). T...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Infect Dis
Main Authors: Ulloa, Erlinda R, Dillon, Nicholas, Tsunemoto, Hannah, Pogliano, Joe, Sakoulas, George, Nizet, Victor
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Major Articles and Brief Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6603980/
https://ncbi.nlm.nih.gov/pubmed/30923801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz128
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