Exercise training increases GAD65 expression, restores the depressed GABA(A) receptor function within the PVN and reduces sympathetic modulation in hypertension

GABAergic inhibitory input within the paraventricular hypothalamic nucleus (PVN) plays a key role in restraining sympathetic outflow. Although experimental evidence has shown depressed GABA(A) receptor function plus sympathoexcitation in hypertension and augmented GABA levels with reduced sympatheti...

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Bibliographische Detailangaben
Veröffentlicht in:Physiol Rep
Hauptverfasser: Ferreira‐Junior, Nilson C., Ruggeri, Adriana, Silva, Sebastião D., Zampieri, Thais T., Ceroni, Alexandre, Michelini, Lisete C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6603325/
https://ncbi.nlm.nih.gov/pubmed/31264387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14107
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