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Exploring Notch Pathway to Elucidate Phenotypic Plasticity and Intra-tumor Heterogeneity in Gliomas

The phenotypic plasticity and self-renewal of adult neural (aNSCs) and glioblastoma stem cells (GSCs) are both known to be governed by active Notch pathway. During development, GSCs can establish differential hierarchy to produce heterogeneous groups of tumor cells belong to different grades, which...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Chowdhury, Saikat, Sarkar, Ram Rup
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602950/
https://ncbi.nlm.nih.gov/pubmed/31263189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45892-8
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