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Exploring Notch Pathway to Elucidate Phenotypic Plasticity and Intra-tumor Heterogeneity in Gliomas

The phenotypic plasticity and self-renewal of adult neural (aNSCs) and glioblastoma stem cells (GSCs) are both known to be governed by active Notch pathway. During development, GSCs can establish differential hierarchy to produce heterogeneous groups of tumor cells belong to different grades, which...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Chowdhury, Saikat, Sarkar, Ram Rup
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602950/
https://ncbi.nlm.nih.gov/pubmed/31263189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45892-8
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