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Hepatic inactivation of the type 2 deiodinase confers resistance to alcoholic liver steatosis
BACKGROUND: A mouse with hepatocyte-specific deiodinase type II (Dio2) inactivation (Alb-D2KO) is resistant to diet-induced obesity, hepatic steatosis and hypertriglyceridemia due to perinatal epigenetic modifications in the liver. This phenotype is linked to low levels of Zfp125, a hepatic transcri...
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| Publicado en: | Alcohol Clin Exp Res |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6602874/ https://ncbi.nlm.nih.gov/pubmed/30908637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.14027 |
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