Early life adversity and blunted stress reactivity as predictors of alcohol and drug use in persons with COMT (rs4680) Val158Met genotypes

BACKGROUND: Risk for alcoholism may be enhanced by exposure to early life adversity (ELA) in persons with genetic vulnerabilities. We examined ELA in the presence of a common variant of the gene for the enzyme catechol-o-methyltransferase (COMT, Val158Met, rs4680) in relation to cortisol reactivity,...

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Опубликовано в: :Alcohol Clin Exp Res
Главные авторы: Lovallo, William R., Cohoon, Andrew J., Sorocco, Kristen H., Vincent, Andrea S., Acheson, Ashley, Hodgkinson, Colin A., Goldman, David
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602827/
https://ncbi.nlm.nih.gov/pubmed/31150143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.14079
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