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Joint impact of early life adversity and COMT Val158Met (rs4680) genotypes on the adult cortisol response to psychological stress

OBJECTIVE: Exposure to stress during critical periods of development can diminish stress reactivity by the hypothalamic-pituitary-adrenocortical axis. Genetic characteristics may further modify this effect of early adversity, leading to a gene-by-environment (G × E) interaction on stress reactivity...

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Detalhes bibliográficos
Publicado no:Psychosom Med
Main Authors: Lovallo, William R., Enoch, Mary-Anne, Sorocco, Kristen H., Vincent, Andrea S., Acheson, Ashley, Cohoon, Andrew J., Hodgkinson, Colin A., Goldman, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489380/
https://ncbi.nlm.nih.gov/pubmed/28452825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PSY.0000000000000481
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