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Opioids: keeping the good, eliminating the bad
Two new studies show that mechanisms mediating the opioid side effects of tolerance, hyperalgesia and physical dependence are mediated spinally and can be dissociated from analgesia. These side effects can be selectively targeted by clinically available drugs without affecting their pain-relieving e...
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| Veröffentlicht in: | Nat Med |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6602584/ https://ncbi.nlm.nih.gov/pubmed/28134927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4277 |
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