Identification and Quantification of Proteoforms by Mass Spectrometry

A proteoform is a defined form of a protein derived from a given gene with a specific amino acid sequence and localized post-translational modifications. In top-down proteomic analyses, proteoforms are identified and quantified through mass spectrometric analysis of intact proteins. Recent technolog...

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Publié dans:Proteomics
Auteurs principaux: Schaffer, Leah V., Millikin, Robert J., Miller, Rachel M., Anderson, Lissa C., Fellers, Ryan T., Ge, Ying, Kelleher, Neil L., LeDuc, Richard D., Liu, Xiaowen, Payne, Samuel H., Sun, Liangliang, Thomas, Paul M., Tucholski, Trisha, Wang, Zhe, Wu, Si, Wu, Zhijie, Yu, Dahang, Shortreed, Michael R., Smith, Lloyd M.
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602557/
https://ncbi.nlm.nih.gov/pubmed/31050378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201800361
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