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mCSM-PPI2: predicting the effects of mutations on protein–protein interactions

Protein–protein Interactions are involved in most fundamental biological processes, with disease causing mutations enriched at their interfaces. Here we present mCSM-PPI2, a novel machine learning computational tool designed to more accurately predict the effects of missense mutations on protein–pro...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Rodrigues, Carlos H M, Myung, Yoochan, Pires, Douglas E V, Ascher, David B
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602427/
https://ncbi.nlm.nih.gov/pubmed/31114883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz383
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