Heterogeneity of transposon expression and activation of the repressive network in human fetal germ cells

Epigenetic resetting in germ cells during development de-represses transposable elements (TEs). piRNAs protect fetal germ cells by targeted mRNA destruction and deposition of repressive epigenetic marks. Here, we provide the first evidence for an active piRNA pathway and TE repression in germ cells...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Development
Main Authors: Reznik, Boris, Cincotta, Steven A., Jaszczak, Rebecca G., Mateo, Leslie J., Shen, Joel, Cao, Mei, Baskin, Laurence, Ye, Ping, An, Wenfeng, Laird, Diana J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Company of Biologists Ltd 2019
Ábhair:
Human Development
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602354/
https://ncbi.nlm.nih.gov/pubmed/30658985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.171157
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla