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Control of Hox transcription factor concentration and cell-to-cell variability by an auto-regulatory switch

The variability in transcription factor concentration among cells is an important developmental determinant, yet how variability is controlled remains poorly understood. Studies of variability have focused predominantly on monitoring mRNA production noise. Little information exists about transcripti...

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Détails bibliographiques
Publié dans:Development
Auteurs principaux: Papadopoulos, Dimitrios K., Skouloudaki, Kassiani, Engström, Ylva, Terenius, Lars, Rigler, Rudolf, Zechner, Christoph, Vukojević, Vladana, Tomancak, Pavel
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602345/
https://ncbi.nlm.nih.gov/pubmed/30642837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.168179
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