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Control of Hox transcription factor concentration and cell-to-cell variability by an auto-regulatory switch

The variability in transcription factor concentration among cells is an important developmental determinant, yet how variability is controlled remains poorly understood. Studies of variability have focused predominantly on monitoring mRNA production noise. Little information exists about transcripti...

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Bibliografische gegevens
Gepubliceerd in:Development
Hoofdauteurs: Papadopoulos, Dimitrios K., Skouloudaki, Kassiani, Engström, Ylva, Terenius, Lars, Rigler, Rudolf, Zechner, Christoph, Vukojević, Vladana, Tomancak, Pavel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists Ltd 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602345/
https://ncbi.nlm.nih.gov/pubmed/30642837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.168179
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