Control of Hox transcription factor concentration and cell-to-cell variability by an auto-regulatory switch

The variability in transcription factor concentration among cells is an important developmental determinant, yet how variability is controlled remains poorly understood. Studies of variability have focused predominantly on monitoring mRNA production noise. Little information exists about transcripti...

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Bibliografiske detaljer
Udgivet i:Development
Main Authors: Papadopoulos, Dimitrios K., Skouloudaki, Kassiani, Engström, Ylva, Terenius, Lars, Rigler, Rudolf, Zechner, Christoph, Vukojević, Vladana, Tomancak, Pavel
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602345/
https://ncbi.nlm.nih.gov/pubmed/30642837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.168179
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