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Control of Hox transcription factor concentration and cell-to-cell variability by an auto-regulatory switch

The variability in transcription factor concentration among cells is an important developmental determinant, yet how variability is controlled remains poorly understood. Studies of variability have focused predominantly on monitoring mRNA production noise. Little information exists about transcripti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Development
Hauptverfasser: Papadopoulos, Dimitrios K., Skouloudaki, Kassiani, Engström, Ylva, Terenius, Lars, Rigler, Rudolf, Zechner, Christoph, Vukojević, Vladana, Tomancak, Pavel
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602345/
https://ncbi.nlm.nih.gov/pubmed/30642837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.168179
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