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Effectors of the spindle assembly checkpoint are confined within the nucleus of Saccharomyces cerevisiae

The spindle assembly checkpoint (SAC) prevents erroneous chromosome segregation by delaying mitotic progression when chromosomes are incorrectly attached to the mitotic spindle. This delay is mediated by mitotic checkpoint complexes (MCCs), which assemble at unattached kinetochores and repress the a...

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Bibliografiske detaljer
Udgivet i:Biol Open
Main Authors: Heasley, Lydia R., DeLuca, Jennifer G., Markus, Steven M.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602339/
https://ncbi.nlm.nih.gov/pubmed/31182632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.037424
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