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Selective inhibition of N-linked glycosylation impairs receptor tyrosine kinase processing

Global inhibition of N-linked glycosylation broadly reduces glycan occupancy on glycoproteins, but identifying how this inhibition functionally impacts specific glycoproteins is challenging. This limits our understanding of pathogenesis in the congenital disorders of glycosylation (CDG). We used sel...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Klaver, Elsenoor, Zhao, Peng, May, Melanie, Flanagan-Steet, Heather, Freeze, Hudson H., Gilmore, Reid, Wells, Lance, Contessa, Joseph, Steet, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602306/
https://ncbi.nlm.nih.gov/pubmed/31101650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.039602
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