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Inhibition of N-Linked Glycosylation Disrupts Receptor Tyrosine Kinase Signaling in Tumor Cells

Receptor tyrosine kinases (RTK) are therapeutic targets for the treatment of malignancy. However, tumor cells develop resistance to targeted therapies through the activation of parallel signaling cascades. Recent evidence has shown that redundant or compensatory survival signals responsible for resi...

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Detalhes bibliográficos
Main Authors: Contessa, Joseph N., Bhojani, Mahaveer S., Freeze, Hudson H., Rehemtulla, Alnawaz, Lawrence, Theodore S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696581/
https://ncbi.nlm.nih.gov/pubmed/18483264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6389
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