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Ceramide synthase inhibition by fumonisins: a perfect storm of perturbed sphingolipid metabolism, signaling, and disease

Fumonisins are mycotoxins that cause diseases of plants and, when consumed by animals, can damage liver, kidney, lung, brain, and other organs, alter immune function, and cause developmental defects and cancer. They structurally resemble sphingolipids (SLs), and studies nearly 30 years ago discovere...

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Veröffentlicht in:J Lipid Res
Hauptverfasser: Riley, Ronald T., Merrill, Alfred H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602133/
https://ncbi.nlm.nih.gov/pubmed/31048407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.S093815
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