Dynamic Changes in Striatal mGluR1 But Not mGluR5 during Pathological Progression of Parkinson's Disease in Human Alpha-Synuclein A53T Transgenic Rats: A Multi-PET Imaging Study

Parkinson's disease (PD) is a prevalent degenerative disorder affecting the CNS that is primarily characterized by resting tremor and movement deficits. Group I metabotropic glutamate receptor subtypes 1 and 5 (mGluR1 and mGluR5, respectively) are important targets for investigation in several...

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發表在:J Neurosci
Main Authors: Yamasaki, Tomoteru, Fujinaga, Masayuki, Kawamura, Kazunori, Furutsuka, Kenji, Nengaki, Nobuki, Shimoda, Yoko, Shiomi, Satoshi, Takei, Makoto, Hashimoto, Hiroki, Yui, Joji, Wakizaka, Hidekatsu, Hatori, Akiko, Xie, Lin, Kumata, Katsushi, Zhang, Ming-Rong
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2016
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Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602033/
https://ncbi.nlm.nih.gov/pubmed/26758830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2289-15.2016
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