l-Lactate-Mediated Neuroprotection against Glutamate-Induced Excitotoxicity Requires ARALAR/AGC1

ARALAR/AGC1/Slc25a12, the aspartate-glutamate carrier from brain mitochondria, is the regulatory step in the malate-aspartate NADH shuttle, MAS. MAS is used to oxidize cytosolic NADH in mitochondria, a process required to maintain oxidative glucose utilization. The role of ARALAR was analyzed in two...

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Argitaratua izan da:J Neurosci
Egile Nagusiak: Llorente-Folch, Irene, Rueda, Carlos B., Pérez-Liébana, Irene, Satrústegui, Jorgina, Pardo, Beatriz
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2016
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Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601833/
https://ncbi.nlm.nih.gov/pubmed/27098689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3691-15.2016
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