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Computational Dissection of Dopamine Motor and Motivational Functions in Humans

Motor dysfunction (e.g., bradykinesia) and motivational deficit (i.e., apathy) are hallmarks of Parkinson's disease (PD). Yet, it remains unclear whether these two symptoms arise from a same dopaminergic dysfunction. Here, we develop a computational model that articulates motor control to econo...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: Le Bouc, Raphaël, Rigoux, Lionel, Schmidt, Liane, Degos, Bertrand, Welter, Marie-Laure, Vidailhet, Marie, Daunizeau, Jean, Pessiglione, Mathias
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601748/
https://ncbi.nlm.nih.gov/pubmed/27335396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3078-15.2016
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