Computational Dissection of Dopamine Motor and Motivational Functions in Humans

Motor dysfunction (e.g., bradykinesia) and motivational deficit (i.e., apathy) are hallmarks of Parkinson's disease (PD). Yet, it remains unclear whether these two symptoms arise from a same dopaminergic dysfunction. Here, we develop a computational model that articulates motor control to econo...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Le Bouc, Raphaël, Rigoux, Lionel, Schmidt, Liane, Degos, Bertrand, Welter, Marie-Laure, Vidailhet, Marie, Daunizeau, Jean, Pessiglione, Mathias
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601748/
https://ncbi.nlm.nih.gov/pubmed/27335396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3078-15.2016
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