Development of a high-throughput solubility screening assay for use in antibody discovery

Poor solubility is a common challenge encountered during the development of high concentration monoclonal antibody (mAb) formulations, but there are currently no methods that can provide predictive information on high-concentration behavior of mAbs in early discovery. We explored the utility of meth...

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Bibliographic Details
Published in:MAbs
Main Authors: Chai, Qing, Shih, James, Weldon, Caroline, Phan, Samantha, Jones, Bryan E.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601704/
https://ncbi.nlm.nih.gov/pubmed/30913963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1589851
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