Tumor-Derived GM-CSF Promotes Granulocyte Immunosuppression in Mesothelioma Patients

PURPOSE: The cross-talk between tumor cells, myeloid cells, and T cells can play a critical role in tumor pathogenesis and response to immunotherapies. Although the etiology of mesothelioma is well understood, the impact of mesothelioma tumor cells on the surrounding immune microenvironment is less...

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Veröffentlicht in:Clin Cancer Res
Hauptverfasser: Khanna, Swati, Graef, Suzanne, Mussai, Francis, Thomas, Anish, Wali, Neha, Yenidunya, Bahar Guliz, Yuan, Constance, Morrow, Betsy, Zhang, Jingli, Korangy, Firouzeh, Greten, Tim F., Steinberg, Seth M., Stetler-Stevenson, Maryalice, Middleton, Gary, De Santo, Carmela, Hassan, Raffit
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601632/
https://ncbi.nlm.nih.gov/pubmed/29602801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-3757
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