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Antibody–drug conjugates for cancer therapy

Antibody–drug conjugates are monoclonal antibodies conjugated to cytotoxic agents. They use antibodies that are specific to tumour cell-surface proteins and, thus, have tumour specificity and potency not achievable with traditional drugs. Design of effective antibody–drug conjugates for cancer thera...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Lancet Oncol
Hauptverfasser: Thomas, Anish, Teicher, Beverly A, Hassan, Raffit
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601617/
https://ncbi.nlm.nih.gov/pubmed/27299281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(16)30030-4
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