Vascular burden and APOE ε4 are associated with white matter microstructural decline in cognitively normal older adults

White matter microstructure can be measured with diffusion tensor imaging (DTI). While increasing age is a predictor of white matter (WM) microstructure changes, roles of other possible modifiers, such as cardiovascular risk factors, APOE ε4 allele status and biological sex have not been clarified....

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Detalhes bibliográficos
Publicado no:Neuroimage
Main Authors: Williams, Owen A., An, Yang, Beason-Held, Lori, Huo, Yuankai, Ferrucci, Luigi, Landman, Bennett A., Resnick, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601608/
https://ncbi.nlm.nih.gov/pubmed/30557663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2018.12.009
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