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Improved monovalent TNF receptor 1-selective inhibitor with novel heterodimerizing Fc

The development of alternative therapeutic strategies to tumor necrosis factor (TNF)-blocking antibodies for the treatment of inflammatory diseases has generated increasing interest. In particular, selective inhibition of TNF receptor 1 (TNFR1) promises a more precise intervention, tackling only the...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Richter, Fabian, Seifert, Oliver, Herrmann, Andreas, Pfizenmaier, Klaus, Kontermann, Roland E.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601568/
https://ncbi.nlm.nih.gov/pubmed/30929560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1596512
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