Integrin α-3 ß-1’s central role in breast cancer, melanoma and glioblastoma cell aggregation revealed by antibodies with blocking activity

Breast cancer, melanoma and glioblastoma cells undergo cell-mediated aggregation and aggregate coalescence in a transparent 3D Matrigel environment. Cells from normal tissue and non-tumorigenic cell lines do not exhibit these behaviors. Here, 266 monoclonal antibodies (mAbs) demonstrated to interact...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Lusche, Daniel F., Klemme, Michael R., Soll, Benjamin A., Reis, Ryan J., Forrest, Cristopher C., Nop, Tiffany S., Wessels, Deborah J., Berger, Brian, Glover, Rebecca, Soll, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601557/
https://ncbi.nlm.nih.gov/pubmed/30810437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1583987
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