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An anti-apoptotic HEK293 cell line provides a robust and high titer platform for transient protein expression in bioreactors
HEK293 transient expression systems are used to quickly generate proteins for research and pre-clinical studies. With the aim of engineering a high-producing host that grows and transfects robustly in bioreactors, we deleted the pro-apoptotic genes Bax and Bak in an HEK293 cell line. The HEK293 Bax...
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| Publicado no: | MAbs |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6601552/ https://ncbi.nlm.nih.gov/pubmed/30907238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1598230 |
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