Randomized Placebo Controlled Trial of Low-Dose Tamoxifen to Prevent Local and Contralateral Recurrence in Breast Intraepithelial Neoplasia

PURPOSE: Tamoxifen administered for 5 years at 20 mg/d is effective in breast cancer treatment and prevention, but toxicity has limited its broad use. Biomarker trials showed that 5 mg/d is not inferior to 20 mg/d in decreasing breast cancer proliferation. We hypothesized that a lower dose given for...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: DeCensi, Andrea, Puntoni, Matteo, Guerrieri-Gonzaga, Aliana, Caviglia, Silvia, Avino, Franca, Cortesi, Laura, Taverniti, Cristiana, Pacquola, Maria Grazia, Falcini, Fabio, Gulisano, Marcella, Digennaro, Maria, Cariello, Anna, Cagossi, Katia, Pinotti, Graziella, Lazzeroni, Matteo, Serrano, Davide, Branchi, Daniela, Campora, Sara, Petrera, Marilena, Buttiron Webber, Tania, Boni, Luca, Bonanni, Bernardo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2019
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601429/
https://ncbi.nlm.nih.gov/pubmed/30973790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.18.01779
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