SIRT3 controls brown fat thermogenesis by deacetylation regulation of pathways upstream of UCP1

OBJECTIVE: Brown adipose tissue (BAT) is important for thermoregulation in many mammals. Uncoupling protein 1 (UCP1) is the critical regulator of thermogenesis in BAT. Here we aimed to investigate the deacetylation control of BAT and to investigate a possible functional connection between UCP1 and s...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Sebaa, Rajaa, Johnson, Jeff, Pileggi, Chantal, Norgren, Michaela, Xuan, Jian, Sai, Yuka, Tong, Qiang, Krystkowiak, Izabella, Bondy-Chorney, Emma, Davey, Norman E., Krogan, Nevan, Downey, Michael, Harper, Mary-Ellen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601363/
https://ncbi.nlm.nih.gov/pubmed/31060926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.04.008
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