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Protein disulfide isomerase enhances tissue factor-dependent thrombin generation

Protein disulfide isomerase (PDI) plays an important role in fibrin generation in vivo, but the underlying mechanism remains largely unknown. In this study, using thrombin generation assay (TGA), we investigated whether PDI contributes to tissue factor (TF)-mediated thrombin generation. Human periph...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Chen, Fengwu, Zhao, Zhenzhen, Zhou, Junsong, Lu, Yi, Essex, David W., Wu, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601344/
https://ncbi.nlm.nih.gov/pubmed/29709484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.04.207
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