Blockade of crizotinib-induced BCL2 elevation in ALK-positive anaplastic large cell lymphoma triggers autophagy associated with cell death

Anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphomas are tumors that carry translocations involving the ALK gene at the 2p23 locus, leading to the expression of ALK tyrosine kinase fusion oncoproteins. Amongst hematologic malignancies, these lymphomas are particular in that they...

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Vydáno v:Haematologica
Hlavní autoři: Torossian, Avedis, Broin, Nicolas, Frentzel, Julie, Daugrois, Camille, Gandarillas, Sarah, Saati, Talal Al, Lamant, Laurence, Brousset, Pierre, Giuriato, Sylvie, Espinos, Estelle
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601090/
https://ncbi.nlm.nih.gov/pubmed/30679328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2017.181966
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