The promise of CD4(+)FoxP3(+) regulatory T-cell manipulation in vivo: applications for allogeneic hematopoietic stem cell transplantation

CD4(+)FoxP3(+) regulatory T cells (Tregs) are a non-redundant population critical for the maintenance of self-tolerance. Over the past decade, the use of these cells for therapeutic purposes in transplantation and autoimmune disease has emerged based on their capacity to inhibit immune activation. B...

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Bibliographic Details
Published in:Haematologica
Main Authors: Copsel, Sabrina, Wolf, Dietlinde, Komanduri, Krishna V., Levy, Robert B.
Format: Artigo
Language:Inglês
Published: Ferrata Storti Foundation 2019
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601084/
https://ncbi.nlm.nih.gov/pubmed/31221786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.198838
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