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Mechanisms of thrombocytopenia in platelet-type von Willebrand disease
Platelet-type von Willebrand disease is an inherited platelet disorder characterized by thrombocytopenia with large platelets caused by gain-of-function variants in GP1BA leading to enhanced GPIbα-von Willebrand factor (vWF) interaction. GPIbα and vWF play a role in megakaryocytopoiesis, thus we aim...
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| Publicat a: | Haematologica |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Ferrata Storti Foundation
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6601082/ https://ncbi.nlm.nih.gov/pubmed/30655369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.200378 |
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