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Persistence of learning-induced synapses depends on neurotrophic priming of glucocorticoid receptors

Stress can either promote or impair learning and memory. Such opposing effects depend on whether synapses persist or decay after learning. Maintenance of new synapses formed at the time of learning upon neuronal network activation depends on the stress hormone-activated glucocorticoid receptor (GR)...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Arango-Lievano, Margarita, Borie, Amelie M., Dromard, Yann, Murat, Maxime, Desarmenien, Michel G., Garabedian, Michael J., Jeanneteau, Freddy
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601006/
https://ncbi.nlm.nih.gov/pubmed/31182610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903203116
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