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Persistence of learning-induced synapses depends on neurotrophic priming of glucocorticoid receptors

Stress can either promote or impair learning and memory. Such opposing effects depend on whether synapses persist or decay after learning. Maintenance of new synapses formed at the time of learning upon neuronal network activation depends on the stress hormone-activated glucocorticoid receptor (GR)...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Arango-Lievano, Margarita, Borie, Amelie M., Dromard, Yann, Murat, Maxime, Desarmenien, Michel G., Garabedian, Michael J., Jeanneteau, Freddy
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601006/
https://ncbi.nlm.nih.gov/pubmed/31182610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903203116
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