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Persistence of learning-induced synapses depends on neurotrophic priming of glucocorticoid receptors

Stress can either promote or impair learning and memory. Such opposing effects depend on whether synapses persist or decay after learning. Maintenance of new synapses formed at the time of learning upon neuronal network activation depends on the stress hormone-activated glucocorticoid receptor (GR)...

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發表在:Proc Natl Acad Sci U S A
Main Authors: Arango-Lievano, Margarita, Borie, Amelie M., Dromard, Yann, Murat, Maxime, Desarmenien, Michel G., Garabedian, Michael J., Jeanneteau, Freddy
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601006/
https://ncbi.nlm.nih.gov/pubmed/31182610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903203116
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