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Correlated protein conformational states and membrane dynamics during attack by pore-forming toxins

Pore-forming toxins (PFTs) are a class of proteins implicated in a wide range of virulent bacterial infections and diseases. These toxins bind to target membranes and subsequently oligomerize to form functional pores that eventually lead to cell lysis. While the protein undergoes large conformationa...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Ponmalar, Ilanila I., Cheerla, Ramesh, Ayappa, K. Ganapathy, Basu, Jaydeep K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600976/
https://ncbi.nlm.nih.gov/pubmed/31189600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1821897116
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