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Elevated dopamine signaling from ventral tegmental area to prefrontal cortical parvalbumin neurons drives conditioned inhibition

Conditioned inhibition is an important process to suppress learned responses for optimal adaptation, but its underlying biological mechanism is poorly understood. Here we used safety learning (SL)/fear discrimination after fear conditioning as a conditioned inhibition model because it demonstrates t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Yan, Rongzhen, Wang, Tianyu, Zhou, Qiang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600914/
https://ncbi.nlm.nih.gov/pubmed/31182594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901902116
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