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A Fast Pairwise Approximation of Solvent Accessible Surface Area for Implicit Solvent Simulations of Proteins on CPUs and GPUs

We propose a pairwise and readily parallelizable SASA-based nonpolar solvation approach for protein simulations, inspired by our previous pairwise GB polar solvation model development. In this work, we developed a novel function to estimate the atomic and molecular SASAs of proteins, which results i...

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Bibliographic Details
Published in:J Chem Theory Comput
Main Authors: Huang, He, Simmerling, Carlos
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600810/
https://ncbi.nlm.nih.gov/pubmed/30303377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.8b00413
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