Epigallocatechin-3-Gallate Prevents Acute Gout by Suppressing NLRP3 Inflammasome Activation and Mitochondrial DNA Synthesis

Gout is a chronic inflammatory disease evoked by the deposition of monosodium urate (MSU) crystals in joint tissues. The nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family pyrin domain containing 3 (NLRP3) inflammasome is responsible for the gout inflammatory symptoms induced...

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Bibliografske podrobnosti
izdano v:Molecules
Main Authors: Lee, Hye Eun, Yang, Gabsik, Park, Youn Bum, Kang, Han Chang, Cho, Yong-Yeon, Lee, Hye Suk, Lee, Joo Young
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600669/
https://ncbi.nlm.nih.gov/pubmed/31174271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24112138
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