Inhibition of NLRP3 inflammasome in tumor microenvironment leads to suppression of metastatic potential of cancer cells

Tumor microenvironment favors tumor cells to promote their growth and metastasis such as migration, invasion, and angiogenesis. IL-1β, one of the inflammatory cytokines released from myeloid cells in tumor microenvironment, plays an important role in development and progress of tumor. The activation...

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Udgivet i:Sci Rep
Main Authors: Lee, Hye Eun, Lee, Jin Young, Yang, Gabsik, Kang, Han Chang, Cho, Yong-Yeon, Lee, Hye Suk, Lee, Joo Young
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706417/
https://ncbi.nlm.nih.gov/pubmed/31439870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48794-x
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